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Author

Michael J. Shelley

2 papers indexed here

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Preprint Oct 2026

Polarization of the Drosophila oocyte by active cortical exchange

Anterior-posterior polarization in the Drosophila oocyte requires posterior localization of oskar mRNA. oskar mRNA is produced in the anteriorly situated nurse cells, moved into the oocyte, and assembled into oskar-Staufen ribonucleoprotein particles (RNPs). These RNPs then move through the oocyte and interact with the...

Mohammadhossein Firouznia, Wen Lu, M. Lakonishok et al. · 0 citations
Open access Aug 2026

Cell size reduction distinctly scales spindle elongation and chromosome segregation in C. elegans

How embryos adapt their internal cellular machinery to reductions in cell size during development remains a fundamental question in cell biology. Here, we use high-resolution lattice light-sheet fluorescence microscopy and automated image analysis to quantify lineage-resolved mitotic spindle and chromosome segregation...

Chukwuebuka William Okafornta, R. Farhadifar, G. Fabig et al. · 0 citations

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