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Michael P. Busch

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Open access Aug 2026

The immunophenotype and proviral landscape of HIV-infected CD4 T cells during antiretroviral therapy

Significance The persistence of HIV in CD4+ T cells during antiretroviral therapy (ART) remains a barrier to cure. To study this reservoir, we developed an open-source DAb-seq platform that sequences proviral DNA and surface epitopes in single cells and profiled ~527,000 CD4 T cells from individuals on ART. HIV-infecte...

C. Delley, Sakshi Shah, Kevin M. Joslin et al. · 0 citations

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