Author

Michael R Verneris

2 papers indexed here

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Open access Aug 2026

Progressive deterioration of adaptive immune repertoires in Down syndrome linked to interferon hyperactivity and lymphoid tissue disorganization

Persons with Down syndrome (DS), the genetic condition caused by trisomy 21 (T21), display strong dysregulation of adaptive immunity, which underlies high risk of complications from infections, widespread autoimmunity, and poor vaccine responses. However, the mechanisms by which T21 dysregulates adaptive immunity acros...

Micah G. Donovan, N. Eduthan, Brian F. Niemeyer et al. · bioRxiv · 0 citations

Open access Jul 2026

Engineered TCR therapy targeting lipid antigens in AML 2306228

Acute myeloid leukemia (AML) is the most common form of adult leukemia and has a poor prognosis with a 5-year overall survival of ∼30%. While CAR-T has revolutionized the treatment of other hematological malignancies, it has been difficult to replicate this same success in AML. Healthy myeloid cells often share e...

Amandip Bangar, B. Linden, Andrew Kent et al. · Journal of Immunology · 0 citations