Open access
Jul 2026
Development and biological validation of a dexamethasone-loaded, PLA-based 3D-printable composite filament for bone tissue engineering
The feasibility of integrating DEXA into a controlled drug release system for bone tissue engineering applications is demonstrated, and the FFF-compatible 1% DEXA–PLA CF retains physicochemical integrity after DEXA incorporation and enables sustained local DEXA delivery within a biologically active concentration range, achieving dual osteogenic and immunomodulatory effects.
S. Bianconi, Cem Asci, Fiona Ott et al.
· International Journal of Bio... · 0 citations