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Author

Michał Mikula

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Open access Aug 2026

Integrated Multi-Omics and Interactome Analysis of CDK8 Inhibition Reveals Erythroid Differentiation Programs and Therapeutic Synergy with BET Blockade in AML

Findings identify CDK8 as a transcriptional node of LSC-associated programs and provide a mechanistic rationale for combined CDK8-BET inhibition in molecularly defined AML subsets, which will require validation in functional LSC assays and primary specimens.

M. Statkiewicz, I. Rumieńczyk, U. Pakulska et al. · 0 citations
Review Open access Aug 2026

Cancer Without a Map: Navigating Cancer of Unknown Primary Through Molecular Profiling.

Evidence indicates that molecularly guided therapy, particularly when integrated with clinicopathological data, can improve survival and expand treatment options beyond empirical chemotherapy.

K. Tałasiewicz, Michał Mikula, Aleksandra Kapała · 0 citations

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