AIM OF THE STUDY
Tumor necrosis factor receptor-associated factors (TRAFs) are cytoplasmic adapter proteins that regulate immune cell signaling downstream of TNF, interleukin-1, and Toll-like receptors. Although preclinical data implicate TRAFs in atherogenesis, their clinical relevance in human disease remains unknown...
M. Gissler, Xin Gu, F. V. D. van der Zalm et al.· Atherosclerosis· 0 citations
AIMS
The etiology of coronary artery Disease (CAD) appears different for men and women, yet insights into underlying sex-specific biological mechanisms are limited. We integrated genomic and proteomic analyses to investigate sex-specific associations of the plasma-proteome with CAD.
METHODS AND RESULTS
In 40,829 UK B...
V. Sier, K. Dimitrova, E. Peters et al.· Cardiovascular Research· 0 citations
Plasma cfRNA was associated with calcification in carotid atherosclerotic plaques and may reflect aspects of underlying plaque biology and require validation in larger, independent populations.
Jian-Ming Wei, T. Lan, Yayuan Zhu et al.· npj Genomic Medicine· 0 citations
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