Open access
Jul 2026
Mechanistic Insights into Autoinhibition of the Human Flippase ATP8B1
It is demonstrated that a minimal peptide spanning residues 1216-1228, which bridges the A- and N-domains in the autoinhibited conformation, is sufficient to inhibit ATPase activity.
Michelle Juknaviciute Laursen, Mathilde Roth, P. Nissen et al.
· Journal of Membrane Biology · 1 citation