Author

Mihaela Bălan-Porcărașu

2 papers indexed here

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Sep 2026

Cooperative β-cyclodextrin/TBD acylation/deacylation in the ring-opening of ε-caprolactone - a 1H NMR and MALDI MS kinetic study.

Cyclodextrins (CDs) are widely employed in supramolecular chemistry for their ability to form inclusion complexes, yet the connection between cyclic ester complexation and its influence on ring-opening processes remains insufficiently understood. Here, we investigate the ring-opening oligomerization of ε-caprolactone (...

Mihaela Bălan-Porcărașu, Diana-Andreea Blaj, C. Peptu · Carbohydrate Polymers · 0 citations

Open access Sep 2026

Metal thiosemicarbazonates as dual mR2 RNR and colchicine-site tubulin inhibitors: from biochemical inhibition to mitotic arrest in MCF-7 breast cancer cells

Cancer cells exploit multiple proliferation pathways, making single-target therapies vulnerable to resistance. Here, a thiosemicarbazone-based strategy is introduced for striking two validated oncotargets, the R2 subunit of ribonucleotide reductase (RNR) and the colchicine site of tubulin, with one agent. Guided by mol...

O. Palamarciuc, Bianca-Iulia Ciubotaru, Alexandru-Constantin Stoica et al. · Inorganic Chemistry Frontier... · 0 citations