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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Mihaela Zavolan

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Open access Aug 2026

PAIP1 couples mRNA export to cytoplasmic mRNP remodeling and poly(A) homeostasis

This work identifies PAIP1 as a metazoan cofactor of the mRNA export ATPase DDX19, and identifies an export-coupled mRNP maturation pathway linking PABP exchange to downstream mRNA metabolism.

D. Overwijn, K. Dörner, Caroline de Almeida et al. · 0 citations
Open access Aug 2026

Mapping the NFYA 3′UTR landscape identifies alternative polyadenylation as a targetable vulnerability in prostate cancer

Findings establish NFYA  3′UTR lengthening in PCa cells via CRISPR/Cas9 or ASOs diminished NF-YA protein levels and suppressed aggressive tumor traits both in vitro and in vivo, and provide proof-of-concept for gene-specific, APA-directed therapeutic strategies.

Giulia Pagani, Chiara Casirati, Cecilia Pandini et al. · 0 citations

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