Author

Mihai-Virgil Boldeanu

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Review Open access Sep 2026

Chronic Occupational Stress and Immune–Inflammatory Dysregulation: Mechanisms, Clinical Consequences, Biomarkers and Implications for Occupational Medicine

Chronic occupational stress is associated with adverse cardiovascular, metabolic, and mental-health outcomes, but the biological evidence linking workplace exposures to immune–inflammatory dysregulation varies in directness and clinical relevance. This narrative review distinguishes findings demonstrated directly in oc...

Ancuța-Ramona Boicea Camen, Mihai-Virgil Boldeanu, D. Caragea et al. · Diagnostics · 0 citations

Review Open access Sep 2026

Shift Work, Circadian Disruption, and Immune Dysregulation: Molecular Links to Gastrointestinal Diseases and Occupational Health Implications

Current evidence linking shift work with gastrointestinal dysfunction and disease is synthesized while distinguishing epidemiological associations from experimental mechanistic evidence and biologically plausible but insufficiently validated relationships, to determine whether occupational, behavioral, or mechanism-bas...

Ancuța-Ramona Boicea Camen, D. Caragea, Mihai-Virgil Boldeanu et al. · Diagnostics · 0 citations

Open access Aug 2026

Dynamic Inflammatory and Erythrocyte-Derived Biomarkers in Newly Diagnosed Multiple Myeloma: A Longitudinal Analysis of Classical and Novel Indices

Baseline inflammatory and erythrocyte-derived indices, including the novel composite markers MCVL and IIC, have limited prognostic utility in multiple myeloma, and dynamic changes in inflammatory biomarkers during treatment may provide more clinically relevant information regarding disease progression.

Alexandra-Ștefania Stroe-Ionescu, L. Boldeanu, A. Pǎtraşcu et al. · Biomedicines · 0 citations

Open access Aug 2026

Prognostic Significance of Oxidative Stress Biomarkers and Novel Hematological Inflammatory Indices in Colorectal Cancer: A Prospective Observational Study

CRC was associated with increased circulating oxidative stress biomarkers, with MDA showing the most consistent relationships with systemic inflammatory parameters and survival outcomes, and MDA is identified as a promising candidate oxidative–inflammatory marker warranting external validation rather than an independen...

R. Marinescu, Daniela Marinescu, A. Ciurea et al. · Medicina · 0 citations

Review Open access Jul 2026

Gut Microbiome Dysbiosis in Atopic Dermatitis: Pathogenic Mechanisms, Gut–Skin Axis Disruption, and Emerging Microbiota-Targeted Therapies

Current evidence supports the gut microbiome as a mechanistically plausible contributor, potential biomarker, and therapeutic target in AD while underscoring the need for longitudinal, phenotype-aware, and externally validated studies before routine clinical translation.

L. Boldeanu, A. Ghenea, Marius-Bogdan Novac et al. · Biomedicines · 0 citations