Prohibitin-1 cysteine-69 plays a sex-dependent role in fatty acid metabolism.
Metabolic diseases are caused by dysregulation of glucose and lipid homeostasis, which relies on the function of adipose tissues. This regulation and the associated pathologies differ between sexes, which remain incompletely understood. Prohibitin-1 (PHB1) has multifaceted tissue-specific functions converging on metabo...