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Author

Miki Kashiwagi

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Open access Sep 2026

Intratumoral Administration of Recombinant Murine Interleukin-12 Prevents Tumor Progression and Bone Invasion.

OBJECTIVE Oral squamous cell carcinoma (OSCC) frequently invades the mandibular bone, leading to metastasis and poor prognosis. This study aimed to evaluate the therapeutic effects of locally administered interleukin-12 (IL-12) using an immunocompetent mouse model mimicking the clinical features of mandibular bone inva...

S. Kasahara, Miki Kashiwagi, Toshihiro Inubushi et al. · 0 citations

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