Milon Kumar Sarkar

Integrated in silico identification of fungal-derived dual-target inhibitors for anti- schistosomal drug discovery

Praziquantel, which has limited efficacy against young parasites and reduces susceptibility, is the principal therapy for schistosomiasis, a neglected tropical illness. This work identified fungal- derived compounds with potential dual inhibitory action against Schistosoma mansoni DHODH and cathepsin B1 using an integr...