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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Milos Pjanic

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Open access Sep 2026

Lifespan single-cell transcriptomic atlas of the human prefrontal cortex

A single-nucleus transcriptomic atlas spanning the human lifespan is used to show that the dorsolateral prefrontal cortex exhibits non-linear, cell-type-specific transcriptional trajectories characterized by dynamic remodelling during development, relative stability in midlife and selective molecular reactivation in la...

Hui Yang, Tereza Clarence, Madeline R. Scott et al. · 4 citations
Open access Sep 2026

Single-cell atlas of transcriptomic vulnerability across brain disorders

A population-scale single-cell transcriptomic atlas of the human dorsolateral prefrontal cortex provides a perspective of the transcriptomic landscape in neurodegenerative and neuropsychiatric disorders, and offers potential targets for therapeutic intervention.

Donghoon Lee, Mikaela Koutrouli, Nicolas Y. Masse et al. · 6 citations
Open access Aug 2026

Plasticity of human microglia and brain perivascular macrophages in aging and Alzheimer’s disease

It is shown that a disease-associated microglial subtype, characterized by elevated GPNMB expression and enriched for polygenic AD risk, expands with AD pathology and shows increased phagocytic activity, and MITF is identified as an upstream regulator required to maintain this microglial state.

Donghoon Lee, James M. Vicari, Christian Porras et al. · 1 citation

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