2026
Engineering a Monomeric Nanopore Scaffold for Multiplexed Protein Detection.
Joshua C. Foster, Min Chen
· Methods in molecular biology · 0 citations
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Open access
Aug 2026
Single-Molecule Nanopore Profiling of p53-TAD’s Conformational Dynamics, Interactions, and Inhibition
The MspA nanopore platform demonstrated using the intrinsically disordered transactivation domain of tumor suppressor p53 (p53-TAD) showed that MspA can stably capture p53-TAD and resolve up to six distinct current states with frequent interconversions, revealing a rich conformational landscape.
David DeCoeur, Samantha A Schultz, Jian-Han Chen et al.
· bioRxiv · 0 citations