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Review Open access Sep 2026

GPER1: A Hidden Key in Cardio-Renal Axis-Unveiling its Therapeutic Potential for Heart and Kidney Disease.

Cardiovascular and kidney diseases are tightly interconnected through a bidirectional cardio-renal axis and exhibit pronounced sex-specific differences, implicating estrogen-associated signaling networks as critical modulators of disease susceptibility and progression. Among these, G protein-coupled estrogen receptor 1...

Chen-Xi Wang, Su-Jie Guo, Yao-Dong Gu et al. · 0 citations

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