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Review Open access Sep 2026

Tumor-associated macrophages beyond M1/M2 in NSCLC: spatially organized programs, therapy resistance, and translational targeting

Tumor-associated macrophages (TAMs) are abundant and functionally diverse components of the lung tumor microenvironment (TME) and are associated with therapeutic response and resistance in non-small cell lung cancer (NSCLC). Durable responses to immune checkpoint inhibitors (ICIs) and targeted therapies remain limite...

Xiao-Long Wang, Zi-Heng Jiang, Qian-Qian Lu et al. · 0 citations

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