Tumor-associated macrophages beyond M1/M2 in NSCLC: spatially organized programs, therapy resistance, and translational targeting
Tumor-associated macrophages (TAMs) are abundant and functionally diverse components of the lung tumor microenvironment (TME) and are associated with therapeutic response and resistance in non-small cell lung cancer (NSCLC). Durable responses to immune checkpoint inhibitors (ICIs) and targeted therapies remain limite...