Min-Ku Song

Integration of GWAS and single-cell analysis for psoriasis identifies disease-associated cell subtypes and therapeutic targets

Psoriasis is a heritable, common chronic autoimmune disorder characterized by cycles of remission and flare-ups. Here, we jointly analyze genomic and single-cell transcriptomic data to elucidate the genetic and molecular architecture of psoriasis. We perform a large-scale genome-wide meta-analysis of individuals of Eur...