Synergistic Stabilization and Bioactivity Enhancement of Collagen by Dual-Terminal Fusion with a central Elastin-like Polypeptide.
The biomedical application of single-type collagens is often constrained by their limited structural stability and biological activity. To address these challenges, we designed a novel fusion protein, designated CEC, using a central elastin-like polypeptide (ELP) to link the human type I and type III collagens. This du...