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Open access Sep 2026

Hex-MASP for mapping the whole-tissue spatial proteome and the intrabrain distribution of monoclonal antibodies

Significance Spatial proteomics at the whole-tissue level is essential for deciphering spatially organized biological regulation yet remains out of reach for most existing methods. Here we introduce hex-MASP (micro-scaffold assisted spatial proteomics), a next-generation spatial proteomics platform that uses a 3D-print...

Shi-Han Huo, Min Ma, S. Qian et al. · 0 citations
Review Jul 2026

Decoding Cardiovascular Disease Through Spatial Proteomics.

An integrated workflow in which untargeted, whole-tissue mapping of thousands of proteins is first used to unbiasedly discover spatial patterns and generate hypotheses by identifying candidate regions and proteins of interest, followed by hypothesis testing and validation using high-precision region-of-interest-based p...

Min Ma, Yingyi Lian, Erfei Shang et al. · 0 citations

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