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Aug 2026

The mechanism of SOX4/IGF2BP3/TRIB3 axis inhibiting autophagy and aggravating liver injury in sepsis.

Sepsis-associated liver injury (SALI) is a serious complication with limited treatment options. While protective autophagy is often suppressed in sepsis, the underlying mechanisms remain unclear. This study investigated whether the SOX4/IGF2BP3/TRIB3 pathway contributes to liver dysfunction by suppressing cytoprotectiv...

Wen-Jun Zhao, Jing Zhang, Liang Zhang et al. · 0 citations

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