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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Min Sun

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Open access Sep 2026

SS-31 Attenuates Lipopolysaccharide-Induced Injury in HK-2 Renal Tubular Epithelial Cells via SIRT3-Mediated Regulation of Mitochondrial Metabolism

Background: The mitochondrial-targeting peptide Elamipretide (SS-31) has shown protective effects against sepsis-associated acute kidney injury (S-AKI). Therefore, we investigated the mechanism underlying its effects on lipopolysaccharide (LPS)-induced injury in renal tubular epithelial cells, with a focus on mitochond...

Xiang-Wei Wu, Meng-Han Shi, Min Sun et al. · 0 citations

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