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Review Open access Sep 2026

Recent variant discoveries and emerging genetic mechanisms in autoinflammatory diseases

Autoinflammatory diseases (AIDs) comprise a heterogeneous group of disorders caused by dysregulated innate immune responses. Over the past decade, advances in next-generation sequencing have markedly expanded the spectrum of disease-associated genes and revealed novel genetic mechanisms, including somatic mosaicism and...

Jin-Yun Chen, Shi-Liang Zhou, Ting Xu et al. · 0 citations

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