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Oct 2026

CircNFIB attenuates hypoxia/reoxygenation-induced ferroptosis in AC16 cardiomyocytes with involvement of the miR-338-3p/GPX4 pathway.

Cardiomyocyte ferroptosis contributes to myocardial ischemia/reperfusion injury, but the upstream noncoding RNA mechanisms remain incompletely defined. This study examined whether nuclear factor I B-derived circular RNA (circNFIB) regulates hypoxia/reoxygenation (H/R)-induced ferroptosis in human ventricular cardiomyoc...

Rong Huang, Jun Wang, Jun-Chen He et al. · 0 citations
Open access Oct 2026

Time-Stable Ferroptosis-Related Candidate Genes in Myocardial Ischemia/Reperfusion Injury Identified by Multi-Time-Point Transcriptomic Analysis: Prioritization of NCF2 Through Public Datasets and AC16 Cell Validation

NCF2 showed the most consistent support across datasets, sample types and AC16 H/R experiments, suggesting it as a prioritized candidate linking ferroptosis-related oxidative stress and myeloid immune activation.

Rong Huang, Jun Wang, Jun-Chen He et al. · 0 citations
Review Open access Jul 2026

Effect of general anesthesia on postoperative outcomes of transcatheter aortic valve implantation in patients: a systematic review and meta-analysis

Objective The optimal mode of anesthesia for patients undergoing transcatheter aortic valve implantation (TAVI) surgery has been controversial recently, especially with the popularization of TAVI in young and low-risk patients and reduced dependence on transesophageal echocardiography (TEE). Beyond general anesthesia (...

Guanzhuo Li, Junchen He, Yating Yang et al. · 0 citations

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