Mine Yalcinkaya Kara

TXNIP and NLRP3 inflammasome markers in major depressive disorder: Associations with remission status and verbal memory.

BACKGROUND Oxidative stress plays a role in the pathophysiology of depression and cognitive dysfunction. Oxidative stress induced NOD-like receptor 3(NLRP3) inflammasome and Thioredoxin-interacting protein (TXNIP) activation may contribute to neuroinflammation in depression. As oxidative stress contributes to insulin r...