Ming Chen

A reactive oxygen species-responsive diclofenac nanogel coating improves the anti-degeneration performance of bioprosthetic heart valves.

The growing burden of valvular heart disease has led to increased use of bioprosthetic heart valves (BHVs), yet limited durability remains a major challenge. Although calcification, chronic inflammation and mechanical injury are recognized contributors to BHVs degeneration, their relative contributions and interactions...