Open access
Oct 2026
Base-mismatched crRNA in CRISPR Enabled Universal One-pot Rapid Nucleic Acid Detection
This cost-effective, adaptable strategy can streamline RPA-CRISPR diagnostics for infectious disease surveillance and convert established two-step assays for Burkholderia pseudomallei and Brucella into one-pot formats.
Jian-Hao Xu, Xin Wang, Bing Yuan et al.
· bioRxiv · 0 citations