Ming-Feng Xiong

UCHL5 stabilizes ALK5 to promote autophagy dependent ferroptosis in osteoarthritis

Ferroptosis is recognized as a key driver in the pathological progression of osteoarthritis (OA), but its regulatory mechanisms remain incompletely understood. To address this gap, we focused on the deubiquitinating enzyme UCHL5, which is implicated in OA progression, to elucidate its function in modulating ferropt...