Single-cell analysis identifies an LDL metabolism–associated myeloid signature and tumor cell–intrinsic ITGA5 in HNSCC
Lipid metabolic reprogramming is a hallmark of tumor progression, yet the role of low-density lipoprotein (LDL) metabolism in head and neck squamous cell carcinoma (HNSCC) remains unclear. This study aimed to systematically characterize LDL metabolism and identify clinically relevant regulators. Integrated...