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Open access Jul 2026

Prediction of axillary lymph node metastasis using a transformer model and multi-omics validation in breast cancer.

Our study developed a multiomics-driven transformer model that combines mammography, MRI, transcriptomic and proteomic data to noninvasively predict axillary lymph node (ALN) metastasis in breast cancer. A total of 2105 patients from 10 institutions were included for model training and validation. The model achieved an...

Xiaodong Liu, Fan Li, Ye Xiang et al. · 0 citations
Review Open access Aug 2026

Metabolic Bottlenecks and Opportunities: Reshaping the Tumor Microenvironment for Cancer Immunotherapy

Metabolic reprogramming constitutes a fundamental hallmark of malignancy, orchestrating a hostile tumor microenvironment (TME) that severely compromises anti-tumor immunity. Despite the transformative success of immune checkpoint blockade and adoptive cell therapies, clinical efficacy is frequently curtailed by the met...

Jia-Ning Zhang, Zi-Mei Tang, Yiran Wang et al. · 0 citations

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