Author

Ming-Jun Zhu

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Review Open access Sep 2026

Therapeutic Targeting of Viral Myocarditis with Natural Products and Herbal Medicines: From Immune-Inflammatory Mechanisms to Clinical Translation

Abstract Viral myocarditis (VMC) is a heterogeneous inflammatory myocardial disease initiated by viral infection and sustained by dysregulated innate and adaptive immunity. Its progression can be viewed as a stage-dependent continuum: virus-triggered macrophage and T-cell dysregulation initiates immune-inflammatory amp...

Wen-Jun Wu, Xue Li, Rui Yu et al. · Journal of Inflammation Rese... · 0 citations

Sep 2026

Sodium tanshinone IIA sulfonate attenuates pulmonary vascular remodeling by targeting DYRK1A in pulmonary hypertension.

BACKGROUND Pulmonary hypertension (PH) is a progressive disorder marked by elevated pulmonary artery (PA) pressure and vascular remodeling, often leading to right heart failure. A key feature is pulmonary artery smooth muscle cells (PASMC) phenotypic switching from a contractile to a synthetic state, which drives media...

Zheng-Wei Dong, Qian-Qian Lu, Zhi-Feng Xue et al. · Phytomedicine · 0 citations

Review Open access Jul 2026

Inflammatory responses driven by neutrophil extracellular traps in cardiovascular diseases: molecular mechanisms, emerging biomarkers, and therapeutic targets

Cardiovascular disease (CVD) remains the leading cause of mortality and disability worldwide, characterized by high incidence, morbidity, and mortality. Although guideline-directed medical therapy has improved clinical outcomes and slowed disease progression to some extent, a substantial residual risk persists, and the...

Aolong Wang, Jing-Jing Wei, Rui Yu et al. · Frontiers in Immunology · 0 citations