Shionone attenuates lipopolysaccharide-induced acute lung injury by inhibiting ferroptosis via Keap1/Nrf2/SLC7A11/GPX4 signaling pathway.
Acute lung injury (ALI) is a respiratory disease with a high mortality rate. Shionone, derived from the Chinese herbal medicine Aster tataricus, has anti-inflammatory and antioxidant effects. However, its protective effect on ALI remains unclear. In this study, we aimed to assess the protective effect of shionone on li...