Lung adenocarcinoma (LUAD) is one of the major subtypes of non-small cell lung cancer (NSCLC), but the molecular mechanisms underlying LUAD initiation and progression remain incompletely understood. In the present study, we identified TRIM46 as a key driver of LUAD progression. TRIM46 is significantly overexpressed i...
Shao-Kun Yu, Xiao Ke, Zhi-Li Liu et al.· Cell Death & Disease· 0 citations
Small cell lung cancer (SCLC) represents the most lethal subtype of lung carcinoma. Platinum-based agents, such as cisplatin and carboplatin, remain the cornerstone of first-line therapy for patients with SCLC, whether administered as chemotherapy alone or in combination with immunotherapy. However, patients frequently...
To monitor changes in the clinical course and adverse events following allogeneic CD19 CAR-NK cell therapy in a patient with relapsed/refractory lupus nephritis (LN). This case report depicts a patient with severe LN refractory to available treatments (including prednisone, mycophenolate mofetil and belimumab) was trea...
Yu Tang, Yan-Run Wang, Wei Shi et al.· Arthritis Research & Therapy· 0 citations
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