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Author

Mingwu Shen

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Aug 2026

Hydroxylated poly(amidoamine) dendrimers mediate the co-delivery of proteins and drugs for enhanced neuroprotection against ischemic stroke.

Development of nanomedicines that can cross blood-brain barrier (BBB) for effective multi-target mitigation of ischemic stroke (IS) is still challenging. Here, we report a hydroxylated poly(amidoamine) dendrimer-based delivery system co-loaded with the immunomodulator fibronectin (FN) protein and the antioxidant neurop...

Siqi Geng, Caiyun Zhang, Zhiqiang Wang et al. · 0 citations
Sep 2026

A Self-Adjuvant Photothermal Carbon Dot-Based Nanovaccine for Multimodal Nasopharyngeal Cancer Treatment and Prophylaxis.

This work provides a promising "full-cycle" nanoplatform that synergistically integrates PTT, chemotherapy, and immunotherapy for both NPC treatment and prophylaxis and generates effective immune protection against subsequent tumor challenge.

Rui-Qi Ji, Yijun Mei, Zhiqiang Wang et al. · 0 citations
Aug 2026

Biomimetic Cancer Cell Membrane-Coated Polymeric Nanogels as a Therapeutic Vaccine for Synergistic Photothermo-Chemo-Immunotherapy of Nasopharyngeal Carcinoma.

The integration of dual-responsive PVCL nanogels, dual ICD induction strategies through combination of photothermo-chemotherapy, and biomimetic membrane cloaking for precision NPC theranostics and immune activation are presented.

Shanbin Wen, Yifan Huang, Xianghao Xiao et al. · 0 citations

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