Open access
Aug 2026
Bisphenol A exacerbates dry eye disease via the CASP1/GSDMD-mediated pyroptotic axis: network toxicology, mendelian randomization, and experimental validation
It is suggested that CASP1 is a central molecular component in dry eye disease pathogenesis and inhibition of CASP1 effectively abrogates this process, suggesting potential avenues for clinical intervention.
Ying-cheng Wang, Chen-Hong Jiang, Yu Zhang et al.
· Frontiers in Pharmacology · 0 citations