Ming Yang

A plasmid-encoded genetic switch orchestrates the bacterial virulence-fitness trade-off to drive antibiotic resistance dissemination

ABSTRACT The global dissemination of multidrug-resistant plasmids poses a major threat to antimicrobial therapy. While these plasmids are known to carry antibiotic resistance genes, how they balance bacterial fitness and virulence to ensure their own persistence and dissemination remains unclear. Here, we identify a pr...