Open access
Oct 2026
ZNF263-mediated transcriptional activation of HK3 alleviates sepsis-associated acute lung injury by regulating the PI3K/AKT/NF-κB pathway
It is revealed for the first time that the transcription factor ZNF263 mitigates inflammation, apoptosis, and oxidative stress in pulmonary epithelial cells during SALI by targeting HK3, a process that is associated with suppression of the PI3K/AKT/NF-κB pathway.
Ming-Yu Zhu, Xiao-Kai Tang, Yao Dong et al.
· Scientific Reports · 0 citations