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Author

Ming-Zhang Wen

2 papers indexed here

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Sep 2026

SlyA directly represses yhcN via a novel binding motif in Salmonella Typhimurium: Implications for motility control.

Salmonella Typhimurium is a prevalent foodborne pathogen worldwide. The MarR family transcriptional regulator SlyA acts as a global modulator of gene expression, yet its specific downstream effectors remain poorly defined. RNA-seq analysis identified 211 genes significantly regulated by SlyA. Notably, the yhcN gene, ex...

Juane Lu, Hong-Fei Fan, Zhi-Yun Liu et al. · 0 citations
#graph neural networks Open access Oct 2026

Discovery of dietary polyphenols targeting the autoinducer-2 quorum sensing system of pathogenic bacteria

Abstract Targeting autoinducer-2 (AI-2) quorum sensing (QS) systems with dietary compounds represents a promising strategy to combat pathogens, yet mechanisms remain elusive. Here, we develop a machine learning-driven framework combining computational screening with multi-level experimental analysis to identify AI-2 qu...

Sheng-Bo Wu, Peng Zhang, Man-Man Wang et al. · 0 citations

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