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Aug 2026

Dual Regulation of ACSL3 by TRIM33-Mediated Ubiquitination and NBR1-Dependent Autophagy: A Therapeutic Target for Cerebral Ischemia-Reperfusion Injury

A novel autophagy–NBR1/TRIM33/TRIM33–ACSL3 regulatory axis that drives ferroptosis in CIRI is revealed, highlighting a promising therapeutic strategy for ischemic stroke through cotargeting autophagy and ferroptosis.

Yue-Qing Yang, Ming Zhao, Yi-Bo Feng et al. · 0 citations

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