Aberrant inflammatory responses are crucial indicators of the onset and progression of diverse pathologies, including metabolic syndromes, autoimmune disorders, and neuroinflammation. The intrinsic intricacy and heterogeneity of these signaling pathways require innovative therapeutic approaches that allow precise immun...
Yumna Zaheer, Syeda Zunaira Bukhari, Unqa Mustafa et al.· Wiley Interdisciplinary Revi...· 0 citations
Development of nanomedicines that can cross blood-brain barrier (BBB) for effective multi-target mitigation of ischemic stroke (IS) is still challenging. Here, we report a hydroxylated poly(amidoamine) dendrimer-based delivery system co-loaded with the immunomodulator fibronectin (FN) protein and the antioxidant neurop...
Siqi Geng, Caiyun Zhang, Zhiqiang Wang et al.· Acta Biomaterialia· 0 citations
This work provides a promising "full-cycle" nanoplatform that synergistically integrates PTT, chemotherapy, and immunotherapy for both NPC treatment and prophylaxis and generates effective immune protection against subsequent tumor challenge.
Rui-Qi Ji, Yijun Mei, Zhiqiang Wang et al.· Advanced Healthcare Material...· 0 citations
The integration of dual-responsive PVCL nanogels, dual ICD induction strategies through combination of photothermo-chemotherapy, and biomimetic membrane cloaking for precision NPC theranostics and immune activation are presented.
Shanbin Wen, Yifan Huang, Xianghao Xiao et al.· ACS Applied Materials and In...· 0 citations
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