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Mingyang Zhou

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Sep 2026

A novel cold-adapted esterase FE2495 from Antarctic Flavobacterium ardleyense A2-1: Biochemical characterization and structural basis for cold-adaptation.

Comparative structural analysis with a thermophilic homolog Est5250 revealed that FE2495 possessed a large catalytic pocket, fewer hydrogen bonds and salt bridges, and a distinct amino acid composition depleted in arginine, providing a possible explanation for its broad temperature tolerance.

Yuan-Fang He, Zeyuan Sun, Sheng-Cai Gao et al. · 0 citations

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