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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Mingzhu Zhao

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Open access Aug 2026

Chemi-Proteome Language Attention Network Empowers Fragment-Based Ligand Interactome and Binding Sites Discovery with Evidence

By learning directly from cellular chemoproteomics, C-PLANK moves beyond isolated interaction prediction toward cellular interaction-state modelling, establishing a computational foundation for future digital-twin frameworks in drug discovery.

Bing-Song Liao, Ji-Xiao He, Mingzhu Zhao et al. · 0 citations
Open access Aug 2026

Discovery of Aurora A/HDAC dual-target inhibitors: broad-spectrum in vitro antitumor activity and in vivo pharmacokinetic limitations.

Z20 is a potent Aurora A/HDAC dual-target inhibitor in vitro, while its pharmacokinetic defects limit clinical potential, which highlights the necessity of optimizing pharmacokinetic profiles for translating in vitro potency to in vivo efficacy.

Li-Rong Zhang, Xuewen Zhang, Jie Zhong et al. · 0 citations

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