Continued remission maintained with decitabine monotherapy in an elderly patient with TP53 multi-hit acute myeloid leukemia relapsed after allogeneic transplantation.
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TP53 mutations define a clinically distinct subset of acute myeloid leukaemia (AML) associated with complex cytogenetics and therapy resistance. We performed a retrospective single-centre analysis of 61 consecutive TP53-altered AML patients undergoing first allogeneic haematopoietic cell transplantation (allo-HCT) at t...
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