Background/Objectives: The rapid emergence of antimicrobial resistance (AMR) among pathogenic bacteria has necessitated the development of alternative therapeutic strategies that target bacterial virulence rather than cell viability. Methods: In this study, the flavonoid myricetin was systematically evaluated for its a...
Abdulrahman S. Bazaid, Nizar H. Saeedi, Mohammed M. Jalal et al.· Pharmaceutics· 0 citations
Neurodegenerative diseases represent a major cause of disability and death, but early diagnosis, prognosis, and therapeutic monitoring are challenging due to biological heterogeneity and the absence of disease-specific biomarkers. Neurofilament light chain (NfL) is a highly sensitive fluid biomarker of neuroaxonal inju...
Overall, this study highlights the potential of ML-guided screening in discovering NEU1 inhibitors targeting mitochondrial dysfunction and fatigue-associated neurodegenerative mechanisms in AD.
Mohd Adnan, Mitesh Patel, Malvi Surti et al.· Journal of Disability Resear...· 0 citations
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