Smart biomimetic biomaterials are increasingly being developed to improve brain repair by providing structural support, localized therapeutic delivery, and biologically active microenvironments that promote tissue integration. However, their performance in the central nervous system is strongly influenced by the neuroi...
Moawiah M. Naffaa· European Cells & Materia...· 0 citations
Neural organoids provide experimentally accessible human systems for studying brain development and disease, but their value depends on more than structural resemblance to neural tissue. This review develops a circuit-inspired framework for examining cell-state dynamics across development, neurodegeneration, and gliobl...
This narrative review examines restoration of immune tolerance as an emerging translational framework in rheumatology, integrating checkpoint agonism, antigen-specific immunotherapy, regulatory cell-based strategies, and immune-reset approaches within a unified therapeutic perspective.
Ola A. Al-Ewaidat, Moawiah M. Naffaa· Rheumato· 0 citations
This perspective provides a unifying conceptual framework for understanding neuroimmune pathology in disorders such as Alzheimer’s disease, multiple sclerosis, stroke, and traumatic brain injury, while also pointing toward next-generation strategies that selectively modulate maladaptive cellular programs and promote re...
Moawiah M. Naffaa· Exploration of Immunology· 0 citations
