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Mohamed E. El Awady

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Open access Jul 2026

Integrated experimental and computational characterization of bioactive metabolites from Streptomyces paradoxus GH53 with antimicrobial, antioxidant, and antitumor activities

Findings suggest that S. paradoxus GH53 represents a promising source of bioactive metabolites for future fractionation, purification, structural confirmation, and compound-level biological evaluation.

Gehad H. El Sayed, A. Fahim, Mohamed Fadel et al. · 0 citations
Aug 2026

Epigenetic Activation of Silent Pathways in Endophytic Aspergillus sp. EGP214 Reveals Porphyrin-Derived Antimicrobial Metabolites Targeting DNA Gyrase: In Vitro and In Silico Evaluation.

The research shows that epigenetic modulation serves as an effective method to activate dormant fungal biosynthetic pathways, which produce valuable secondary compounds with antimicrobial and antioxidant properties.

A. Abd-elaziz, Mai A.M.A. Mwaheb, Gehad H. El Sayed et al. · 0 citations