Review
Open access
Sep 2026
Patient-derived tumor organoid co-culture systems as translational platforms for cancer immunotherapy and precision oncology
The tumor microenvironment (TME) is a dynamic and immunosuppressive niche that critically governs cancer progression, immune evasion, and therapeutic resistance. Accurately modeling tumor–immune interactions in vitro is therefore essential for advancing our understanding of cancer biology and accelerating the developme...
Mohamed Gadelkarim, Ahmed Elsayed, Tasneem Abaza et al.
· Clinical Cancer Bulletin · 0 citations