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Author

Mohamed M. Khalifa

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Review Open access Sep 2026

VEGFR-2 as a druggable target: recent advances (2025) in the development of five-membered heterocyclic anticancer agents.

This comprehensive review systematically examines recent advances in the rational design, synthesis, and biological evaluation of five-membered heterocyclic scaffolds, thiadiazol, oxazole, thiazole, thiazole, and pyrrole, as well as pyrazole and imidazole-based inhibitors as novel VEGFR-2 inhibitors.

Mohamed M. Khalifa, Ibtehal Naseer Salman, Reyadh Jassem · 0 citations

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