Integrated biomarkers of oxidative stress NLRP3 inflammasome and kynurenine pathway reflect disease severity and diagnostic discrimination in depression
Serum levels of kynurenine, NLRP3, and 8-OHdG are all markedly increased in depression and together offer helpful diagnostic data, implying potential utility as complementary biological markers for diagnosing depression and describing its underlying pathophysiology, notwithstanding their modest relationships with symptom severity.