INTRODUCTION
Inflammation and oxidative stress play important roles in the development of various chronic diseases, necessitating compounds with dual therapeutic potential.
METHODS
A series of (E)-7-hydroxy-4-methyl-6-(3-(substituted phenyl)acryloyl)-2H-chromen-2-one (7a-m) were synthesized starting from 7-hydroxy-4-...
Dalaa Ali El-Jadayel, Husna Khalifa Al-Busaidi, Zainab Hamood Al-Balushi et al.· Anti-Inflammatory & Anti-All...· 0 citations
Rational design strategies for rhodanine-based heterocycles and their therapeutic potential as antibacterial, anti-diabetes, anti-Alzheimer’s, anticancer, anthelmintic, anti-obesity, and against COVID-19 are discussed.
R. Nath, Lakshminarayan Das, Arka Chakraborty et al.· Phosphorus Sulfur and Silico...· 0 citations
Heterocyclic scaffolds are vital to medicinal chemistry due to their versatility, diversity, and ability to target various biological molecules. This review covers advances in designing and synthesizing bioactive heterocycles, highlighting structure-based drug design (SBDD) and ligand-based drug design (LBDD) approache...
Debajit Dewan, Bhupender Nehra, R. Nath et al.· Future Medicinal Chemistry· 0 citations
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